Welcome to ORIEMS FIT Edible Insights, where we bring you the latest research findings on food and health!

Today, we're exploring a fascinating study about chia seeds and their potential impact on health, especially for overweight women.

This post is designed to help you understand the study in the simplest way possible.

(Scroll to the end of each post to find a link to the original study, often with full PDFs—perfect for building your research collection.)

What’s the Research Title?

The original title of the research is: "Chia Seed Supplementation and Disease Risk Factors in Overweight Women: A Metabolomics Investigation."

Who Conducted This Study?

• Lead Researcher: Dr. David C. Nieman.
• Research Team Affiliations: Appalachian State University (USA) and the Dole Nutrition Research Laboratory (USA).
• Year: 2012.

Why Is the Research Source Trustworthy?

The chia seed research discussed earlier was published in The Journal of Alternative and Complementary Medicine, a well-established journal founded in 1995. It is known for featuring rigorous studies on health, wellness, and nutrition.

The research was conducted at Appalachian State University, established in 1899, and the Dole Nutrition Research Laboratory, a world-class facility dedicated to food science and innovation. These institutions are located in North Carolina, USA, and are recognized for their academic excellence and contributions to nutrition and health sciences.

The research team was led by Dr. David C. Nieman, a renowned scientist with decades of experience in nutrition, exercise science, and metabolism. Dr. Nieman’s work is highly cited, and he is affiliated with the Human Performance Laboratory, a prestigious research center focused on advancing health through innovative studies.

What Was the Study About?

The study aimed to find out:

1. Does eating chia seeds (milled or whole) improve health markers like inflammation, cholesterol, and body composition?
2. Can chia seeds help postmenopausal, overweight women reduce disease risks?

Who Participated in the Study?

• Participants: 56 postmenopausal women aged 49–75 years.
• Criteria: Overweight (BMI ≥ 25), no chronic diseases, and no use of anti-inflammatory drugs or supplements.

How Was the Study Done?

1. The women were divided into three groups:
   • Milled chia seed group (14 participants).
   • Whole chia seed group (16 participants).
   • Placebo (poppy seed) group (26 participants).
2. They consumed 25 grams of their assigned supplement daily for 10 weeks.
3. The supplements were added to common foods like yogurt or beverages.
4. Health markers were measured before and after the 10 weeks.

What Did the Study Find?

1. Positive Changes in Omega-3 Fatty Acids

• The milled chia seed group showed:
  • 58% increase in alpha-linolenic acid (ALA), a key omega-3 fatty acid. ALA rose from baseline levels of approximately 67 µg/mL to 106 µg/mL over 10 weeks.
  • 39% increase in eicosapentaenoic acid (EPA), another omega-3, rising from about 0.72 µg/mL to 1.0 µg/mL.
• The whole chia seed group had no significant increases in ALA or EPA.
• The placebo group showed no changes in these omega-3 levels.

2. Other Health Markers Remained Stable

• Body Weight: There were no significant changes. Average body weight remained stable at ~88–90 kg across all groups.
• Body Fat Percentage: No notable differences, with levels remaining around 37% across all groups.
• Cholesterol Levels: Serum cholesterol levels stayed at ~5.4 mmol/L, with no improvement across the groups.
• Inflammation Markers: Key inflammation markers, such as C-reactive protein (CRP) and interleukin-6 (IL-6), showed no significant changes.
• Blood Pressure: Systolic blood pressure stayed steady at ~140 mm Hg.

3. Metabolomics Analysis

• Despite the increased omega-3 levels in the milled chia seed group, there were no measurable changes in global or targeted metabolomic profiles linked to disease risk or inflammation.

Why Are These Findings Important?

What Does This Mean for Omega-3 Intake?

• Milled chia seeds are far more effective than whole chia seeds at boosting omega-3 fatty acids (ALA and EPA) in the body. This is important for people who rely on plant-based sources for these essential nutrients.

What’s the Catch?

• While omega-3 levels increased, the short 10-week duration may not have been enough to observe significant changes in other health markers like inflammation or blood pressure.

What Does This Mean for You?

• If you want to increase your omega-3 intake:
  • Choose milled chia seeds. They are absorbed better than whole seeds.
  • Incorporate them regularly in your diet over a longer period for potential long-term benefits.
  • Or simply putting chia seeds in a blender with water and blending them. (If you enjoy a tangy flavor, you can also add a splash of apple cider vinegar for a refreshing and health-boosting drink!)
• Chia seeds are a nutrient powerhouse but may not offer quick fixes for weight loss or disease risk reduction.

Want to Explore the Study?

Here’s the original research for more details:
Title: Chia Seed Supplementation and Disease Risk Factors in Overweight Women: A Metabolomics Investigation.
Link: Study Source

This study is hosted by reputable research institutions and published in a trusted journal, making it a reliable source of information.

What Do You Think?

Have you tried chia seeds? Did they make you feel healthier or more energized? Share your experiences in the comments! If you have questions about food or want us to simplify other studies, let us know—we’re here to help!

This post is part of the ORIEMS FIT Edible Insights series, where we simplify food research for everyday readers. Our mission is to inspire curiosity and encourage self-learning. Share this post with your friends and family—you might spark a new health habit!

Disclaimer: This blog post is for informational and recreational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new treatment. For full details, visit our disclaimer.